Njengamanje, izimboni eziningi zamabhizinisi nezikhungo zomphakathi zinama-laboratories azo. Futhi la ma-laboratories anezinhlobonhlobo zezinto zokuhlola zokuhlola eziqhubekayo nsuku zonke. Kungenzeka ukuthi ukuhlolwa ngakunye kuzokhiqiza inani elihlukile nezinhlobo zezinto zokuhlola ezisele zinamathele ezingilazini. Ngakho-ke, ukuhlanzwa kwezinto ezisele zokuhlola sekuyingxenye engenakugwenywa yomsebenzi wansuku zonke we-laboratories.

Kuyaqondakala ukuthi ukuze kuxazululwe ukungcola okusele kokuhlola ezitsheni zengilazi, amalabhorethri amaningi kufanele atshale imali eningi yokucabanga, amandla abasebenzi kanye nezinsizakusebenza, kodwa imiphumela ivame ukungagculisi. Ngakho-ke, ukuhlanzwa kwezinsalela zokuhlola ezitsheni zengilazi kungaba kanjani okuphephile futhi okusebenzayo? Eqinisweni, uma singathola izinyathelo zokuphepha ezilandelayo futhi siziphathe kahle, le nkinga izoxazululwa ngokwemvelo.

Okokuqala: Yiziphi izinsalela ezivame ukushiywa ezingilazini zaselabhorethri?

Ngesikhathi sokuhlola, imfucuza emithathu ivame ukukhiqizwa, okungukuthi igesi engcolile, uketshezi olungcolile, kanye nezinto eziqinile ezingcolile. Okungukuthi, ukungcola okusele okungenalo inani lokuhlola. Ezitsheni zengilazi, izinsalela ezivame kakhulu uthuli, ama-lotion okuhlanza, izinto ezincibilika emanzini, kanye nezinto ezingancibiliki.

Phakathi kwazo, izinsalela ezincibilikayo zifaka phakathi i-alkali yamahhala, udayi, izinkomba, i-Na2SO4, i-NaHSO4 solids, ama-trace e-iodine kanye nezinye izinsalela eziphilayo; izinto ezingancibiliki zifaka phakathi i-petrolatum, i-phenolic resin, i-phenol, i-grease, i-ointment, i-protein, amabala egazi, i-cell culture medium, i-fermentation residue, i-DNA ne-RNA, i-fiber, i-metal oxide, i-calcium carbonate, i-sulfide, usawoti wesiliva, insipho yokwenziwa kanye nokunye ukungcola. Lezi zinto zivame ukunamathela ezindongeni zengilazi zaselabhorethri ezifana namashubhu okuhlola, ama-burette, amaflaski e-volumetric, nama-pipettes.

Akunzima ukuthola ukuthi izici eziphawulekayo zezinsalela zengilazi ezisetshenziswe ekuhlolweni zingafingqwa kanje: 1. Kunezinhlobo eziningi; 2. Izinga lokungcola lihlukile; 3. Isimo siyinkimbinkimbi; 4. Sinobuthi, siyagqwala, siyaqhuma, siyathelelana nezinye izingozi.

Okwesibili: Yimiphi imiphumela emibi yezinsalela zokuhlola?

Izici ezimbi 1: ukuhlolwa kwehlulekile. Okokuqala, ukuthi ngabe ukucubungula kwangaphambi kokuhlolwa kuyahlangabezana yini nezindinganiso kuzothinta ngqo ukunemba kwemiphumela yokuhlola. Namuhla, amaphrojekthi okuhlola anezidingo eziqinile kakhulu zokunemba, ukulandeleka, kanye nokuqinisekiswa kwemiphumela yokuhlola. Ngakho-ke, ukuba khona kwezinsalela kuzobangela izici eziphazamisayo emiphumeleni yokuhlola, futhi ngaleyo ndlela ngeke kuphumelele ekufezeni injongo yokuthola ukuhlola.

Izici ezimbi 2: insalela yokuhlola inezinsongo eziningi ezibalulekile noma ezingaba khona emzimbeni womuntu. Ikakhulukazi, eminye imithi evivinyiwe inezici zamakhemikhali ezifana nobuthi kanye nokuguquguquka, futhi ukunganaki okuncane kungalimaza ngqo noma ngokungaqondile impilo yomzimba neyengqondo yabantu abathintana nabo. Ikakhulukazi ezinyathelweni zokuhlanza amathuluzi engilazi, lesi simo asivamile.

Umphumela omubi 3: Ngaphezu kwalokho, uma izinsalela zokuhlola zingenakukwazi ukuphathwa kahle nangokuphelele, zizongcolisa kakhulu indawo yokuhlola, ziguqule umoya nemithombo yamanzi zibe yimiphumela engenakuguqulwa. Uma amalabhorethri amaningi efuna ukuthuthukisa le nkinga, akunakugwenywa ukuthi izothatha isikhathi, idinge futhi ibize kakhulu... futhi lokhu sekukhuphuke kwaba yinkinga efihliwe ekuphathweni nasekusebenzeni kwelabhorethri.

Okwesithathu: Yiziphi izindlela zokubhekana nezinsalela zokuhlola zezinto zengilazi?

Ngokuphathelene nezinsalela zengilazi zelebhu, imboni isebenzisa kakhulu izindlela ezintathu: ukuwasha ngesandla, ukuhlanza nge-ultrasound, kanye nokuhlanza umshini wokuwasha wengilazi okuzenzakalelayo ukuze kufezwe injongo yokuhlanza. Izici zalezi zindlela ezintathu yilezi ezilandelayo:

Indlela 1: Ukuwasha ngesandla

Ukuhlanza ngesandla kuyindlela eyinhloko yokugeza nokuhlanza ngamanzi agelezayo. (Ngezinye izikhathi kuyadingeka ukusebenzisa i-lotion elungiselelwe kusengaphambili kanye namabhulashi e-test tube ukusiza) Yonke inqubo idinga abahloli ukuthi bachithe amandla amaningi, amandla omzimba, nesikhathi ukuze baqedele injongo yokususa izinsalela. Ngesikhathi esifanayo, le ndlela yokuhlanza ayikwazi ukubikezela ukusetshenziswa kwezinsizakusebenza zamandla kagesi. Enqubweni yokuwasha ngesandla, idatha ebalulekile yenkomba efana nokushisa, ukuhanjiswa kwamandla, kanye nenani le-pH kunzima kakhulu ukufeza ukulawula kwesayensi nokusebenzayo, ukurekhoda, kanye nezibalo. Futhi umphumela wokugcina wokuhlanza wezinto zengilazi uvame ukungakwazi ukuhlangabezana nezidingo zokuhlanzeka kokuhlolwa.

Indlela 2: Ukuhlanza nge-Ultrasonic

Ukuhlanzwa kwe-Ultrasonic kusetshenziswa ezitsheni zengilazi ezincane (hhayi amathuluzi okulinganisa), njengezitsha ze-HPLC. Ngenxa yokuthi lolu hlobo lwezitsha zengilazi alulungele ukuhlanza ngebhulashi noma lugcwaliswe ngoketshezi, kusetshenziswa ukuhlanzwa kwe-ultrasonic. Ngaphambi kokuhlanzwa kwe-ultrasonic, izinto ezincibilikayo emanzini, ingxenye yezinto ezingancibiliki kanye nothuli olusezitsheni zengilazi kufanele kuhlanzwe ngamanzi, bese kufakwa insipho ethile, kuhlanzwe nge-ultrasonic imizuzu eyi-10-30, uketshezi lokuwasha kufanele luhlanzwe ngamanzi, bese kuhlanzwa Ukuhlanzwa kwe-ultrasonic ngamanzi izikhathi ezi-2 kuya kwezi-3. Izinyathelo eziningi kule nqubo zidinga imisebenzi yesandla.

Kufanele kugcizelelwe ukuthi uma ukuhlanzwa kwe-ultrasound kungalawulwa kahle, kuzoba nethuba elikhulu lokubangela imifantu kanye nomonakalo esitsheni sengilazi esihlanziwe.

Indlela 3: I-washer yengilazi ezenzakalelayo

Umshini wokuhlanza okuzenzakalelayo usebenzisa ukulawulwa kwe-microcomputer okuhlakaniphile, ufanelekela ukuhlanzwa okuphelele kwezinhlobo ezahlukene zengilazi, usekela ukuhlanzwa okuhlukahlukene, kanye nenqubo yokuhlanza ijwayelekile futhi ingakopishwa futhi idatha ingalandelelwa. Umshini wokuwasha amabhodlela ozenzakalelayo awugcini nje ngokukhulula abacwaningi emsebenzini oyinkimbinkimbi wezandla wokuhlanza izingilazi kanye nezingozi zokuphepha ezifihliwe, kodwa futhi ugxila emisebenzini yocwaningo lwesayensi ebaluleke kakhulu. ngoba wonga amanzi, ugesi futhi uluhlaza kakhulu Ukuvikelwa kwemvelo kuye kwandisa izinzuzo zomnotho kulo lonke ilabhorethri esikhathini eside. Ngaphezu kwalokho, ukusetshenziswa komshini wokuwasha amabhodlela okuzenzakalelayo ngokuphelele kusiza kakhulu ezingeni eliphelele lelabhorethri ukuze kufezwe isitifiketi se-GMP \ FDA kanye nemininingwane, okuzuzisa ekuthuthukisweni kwelabhorethri. Ngamafuphi, umshini wokuwasha amabhodlela ozenzakalelayo ugwema ngokusobala ukuphazamiseka kwamaphutha azimele, ukuze imiphumela yokuhlanza ibe nembambo futhi ifane, kanye nokuhlanzeka kwezitsha ngemva kokuhlanza kube okuphelele futhi okufanele!